PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE

Elian, Mohamed A.; AbdelHafiz, Ibrahim S.; AbdElReheim, Mohamed A.M.

doi:10.21608/sinjas.2014.78457

PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE

Authors

Mohamed A. Elian
Ibrahim S. AbdelHafiz
Mohamed A.M. AbdElReheim

Dept. Chem., Fac. Educ., Suez Canal Univ., Arish, Egypt.

10.21608/sinjas.2014.78457

Abstract

A series of new thioxopyrimidine, 4H-pyrans, pyranopyridine and pyranopyrimidine derivatives with expected biological activity have been prepared through the reaction of 6-phenyl-2-thioxo-2,3-dihydropyrimidin-4(5H)-one 4 and 7-Amino-5-(4-chlorophenyl)-4-phenyl-2-thioxo-2,5-dihydro-1H-pyrano[2,3-d]pyrimidine-6-carbonitrile 11b with some electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, 1H-NMR and mass spectral studies.

Keywords

Thioxopyrimidine
4H-pyrans
pyranopyridine and pyranopyrimidine

Main Subjects

General Applied Sciences

PYRIMIDINETHIONES AS BUILDING BLOCKS IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF PYRANO[2,3-D]PYRIMIDINE, CHROMENO[2,3-D]PYRIMIDINE, PYRIDO[3',2':5,6]PYRANO[2,3-B]PYRIDINE AND PYRIMIDO[5',4':5,6]PYRANO[2,3-D]PYRIMIDINE

Volume 3, Issue 2August 2014Pages 51-62

Files

Share

How to cite

Statistics

Volume 3, Issue 2
August 2014
Pages 51-62