UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST

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Dept. Chem., Fac. Sci, Arish Univ., Egypt.

Abstract

Many heterocyclic compounds were prepared from the reaction of 2-imino-6-phenyl-2,3-dihydropyrimidin-4(5H)-one 4 with some bifunctional nucleophiles and electrophiles reagents under mild conditions .The structure of the synthesized compounds were established via their elemental and spectral analysis. Some of the products were also screened in vitro for their biological activity.

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Sinai Journal of Applied Sciences
Volume 6, Issue 2
August 2017
Pages 213-222

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